Article
Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism.
Biological psychiatry - 1 Mar 2012
Fernandez Thomas V, Sanders Stephan J, Yurkiewicz Ilana R, Ercan-Sencicek A Gulhan, Kim Young-Shin, Fishman Daniel O, Raubeson Melanie J, Song Youeun, Yasuno Katsuhito, Ho Winson S C, Bilguvar Kaya, Glessner Joseph, Chu Su Hee, Leckman James F, King Robert A, Gilbert Donald L, Heiman Gary A, Tischfield Jay A, Hoekstra Pieter J, Devlin Bernie, Hakonarson Hakon, Mane Shrikant M, Günel Murat, State Matthew W
Abstract excerpt
BACKGROUND: Studies of copy number variation (CNV) have characterized loci and molecular pathways in a range of neuropsychiatric conditions. We analyzed rare CNVs in Tourette syndrome (TS) to identify novel risk regions and relevant pathways, to evaluate burden of structural variation in cases ve...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.