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Article

REF4 and RFR1, subunits of the transcriptional coregulatory complex mediator, are required for phenylpropanoid homeostasis in Arabidopsis.

The Journal of biological chemistry - 17 Feb 2012

Bonawitz Nicholas D, Soltau Whitney L, Blatchley Michael R, Powers Brendan L, Hurlock Anna K, Seals Leslie A, Weng Jing-Ke, Stout Jake, Chapple Clint

Abstract excerpt

The plant phenylpropanoid pathway produces an array of metabolites that impact human health and the utility of feed and fiber crops. We previously characterized several Arabidopsis thaliana mutants with dominant mutations in REDUCED EPIDERMAL FLUORESCENCE 4 (REF4) that cause dwarfing and decrease...

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Identifiers

PMID: 22167189
DOI: 10.1074/jbc.M111.312298
PMCID: PMC3285322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22167189-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

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REF4 and RFR1, subunits of the transcriptional coregulatory complex mediator, are required for phenylpropanoid homeostasis in Arabidopsis.PMID 22167189Read ↗

Mediator Complex Subunits MED2, MED5, MED16, and MED23 Genetically Interact in the Regulation of Phenylpropanoid Biosynthesis.Semantic proximity Read ↗

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Semidominant mutations in reduced epidermal fluorescence 4 reduce phenylpropanoid content in Arabidopsis.Semantic proximity Read ↗

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Transcriptome Analysis of Four Arabidopsis thaliana Mediator Tail Mutants Reveals Overlapping and Unique Functions in Gene Regulation.Semantic proximity Read ↗

Mediator complex proteins are required for diverse developmental processes.Semantic proximity Read ↗

Loss of FERULATE 5-HYDROXYLASE Leads to Mediator-Dependent Inhibition of Soluble Phenylpropanoid Biosynthesis in Arabidopsis.Semantic proximity Read ↗

Redox regulation of the MED28 and MED32 mediator subunits is important for development and senescence.Semantic proximity Read ↗

PFT1, a transcriptional Mediator complex subunit, controls root hair differentiation through reactive oxygen species (ROS) distribution in Arabidopsis.Semantic proximity Read ↗

Changes in secondary metabolism and deposition of an unusual lignin in the ref8 mutant of Arabidopsis.Semantic proximity Read ↗

The mediator complex subunit PFT1 interferes with COP1 and HY5 in the regulation of Arabidopsis light signaling.Semantic proximity Read ↗

Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate brassinosteroid signaling and plant architecture in rice.Semantic proximity Read ↗

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