Article
The NTD Nanoscope: potential applications and implementations.
BMC bioinformatics - 18 Oct 2011
Winters-Hilt Stephen, Horton-Chao Evenie, Morales Eric
Abstract excerpt
BACKGROUND: Nanopore transduction detection (NTD) offers prospects for a number of highly sensitive and discriminative applications, including: (i) single nucleotide polymorphism (SNP) detection; (ii) targeted DNA re-sequencing; (iii) protein isoform assaying; and (iv) biosensing via antibody or aptamer coupled molecules. Nanopore event transduction involves single-molecule biophysics, engineered information...
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