Article
SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2012
Carreño Oriel, Corominas Roser, Fernández-Morales Jessica, Camiña Montserrat, Sobrido María-Jesús, Fernández-Fernández José Manuel, Pozo-Rosich Patricia, Cormand Bru, Macaya Alfons
Abstract excerpt
The transient receptor potential (TRP) superfamily of non-selective cationic channels are involved in several processes plausibly relevant to migraine pathophysiology, including multimodal sensory and pain perception, central and peripheral sensitization, and regulation of calcium homeostasis. With the aim of identifying single nucleotide polymorphisms (SNPs) in TRP genes that may confer increased genetic...
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