Article
Mixed infection with cagA positive and cagA negative strains of Helicobacter pylori lowers disease burden in The Gambia.
PloS one - 1 Jan 2011
Secka Ousman, Antonio Martin, Berg Douglas E, Tapgun Mary, Bottomley Christian, Thomas Vivat, Walton Robert, Corrah Tumani, Thomas Julian E, Adegbola Richard A
Abstract excerpt
BACKGROUND: The prevalence of Helicobacter pylori including strains with putatively virulent genotypes is high, whereas the H. pylori-associated disease burden is low, in Africa compared to developed countries. In this study, we investigated the prevalence of virulence-related H. pylori genotypes and their association with gastroduodenal diseases in The Gambia. METHODS AND FINDINGS: DNA extracted from biopsies...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antigens, Bacterial
- Bacterial Proteins
- Child
- Coinfection
- Cost of Illness
- Gambia
- Genes, Bacterial