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Article

The 2008-2009 H1N1 influenza virus exhibits reduced susceptibility to antibody inhibition: Implications for the prevalence of oseltamivir resistant variant viruses.

Antiviral research - 1 Jan 2012

Wu Wai Lan, Lau Siu-Ying, Chen Yixin, Wang Genyan, Mok Bobo Wing-Yee, Wen Xi, Wang Pui, Song Wenjun, Lin Tianwei, Chan Kwok-Hung, Yuen Kwok-Yung, Chen Honglin

Abstract excerpt

A naturally-occurring H275Y oseltamivir resistant variant of influenza A (H1N1) virus emerged in 2007, subsequently becoming prevalent worldwide, via an undetermined mechanism. To understand the antigenic properties of the H275Y variant, oseltamivir resistant and susceptible strains of H1N1 viruses were analyzed by hemagglutination inhibition (HI) and microneutralization assays. HI analysis with H1-positive sera...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22138712
DOI: 10.1016/j.antiviral.2011.11.006
PMCID: PMC3243069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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