Article
Towards an integrative view of virus phenotypes.
Nature reviews. Microbiology - 1 Feb 2022
DeLong John P, Al-Sammak Maitham A, Al-Ameeli Zeina T, Dunigan David D, Edwards Kyle F, Fuhrmann Jeffry J, Gleghorn Jason P, Li Hanqun, Haramoto Kona, Harrison Amelia O, Marston Marcia F, Moore Ryan M, Polson Shawn W, Ferrell Barbra D, Salsbery Miranda E, Schvarcz Christopher R, Shirazi Jasmine, Steward Grieg F, Van Etten James L, Wommack K Eric
Abstract excerpt
Understanding how phenotypes emerge from genotypes is a foundational goal in biology. As challenging as this task is when considering cellular life, it is further complicated in the case of viruses. During replication, a virus as a discrete entity (the virion) disappears and manifests itself as a metabolic amalgam between the virus and the host (the virocell). Identifying traits that unambiguously constitute a...
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