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Article

Dengue-1 Virus Clade Replacement in Thailand Associated with Enhanced Mosquito Transmission

2 Dec 2011

Abstract excerpt

Dengue viruses (DENV) are characterized by extensive genetic diversity and can be organized in multiple, genetically distinct lineages that arise and die out on a regular basis in regions where dengue is endemic. A fundamental question for understanding DENV evolution is the relative extent to which stochastic processes (genetic drift) and natural selection acting on fitness differences among lineages contribute...

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PMID: 22130539
DOI: 10.1128/jvi.06458-11

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