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Article

Specific capture and whole-genome sequencing of viruses from clinical samples.

PloS one - 1 Jan 2011

Depledge Daniel P, Palser Anne L, Watson Simon J, Lai Imogen Yi-Chun, Gray Eleanor R, Grant Paul, Kanda Ravinder K, Leproust Emily, Kellam Paul, Breuer Judith

Abstract excerpt

Whole genome sequencing of viruses directly from clinical samples is integral for understanding the genetics of host-virus interactions. Here, we report the use of sample sparing target enrichment (by hybridisation) for viral nucleic acid separation and deep-sequencing of herpesvirus genomes directly from a range of clinical samples including saliva, blood, virus vesicles, cerebrospinal fluid, and tumour cell...

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Source

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Identifiers

PMID: 22125625
DOI: 10.1371/journal.pone.0027805
PMCID: PMC3220689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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