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The Polyketide Pks1 Contributes to Biofilm Formation in Mycobacterium tuberculosis

29 Nov 2011

Abstract excerpt

Infections caused by biofilms are abundant and highly persistent, displaying phenotypic resistance to high concentrations of antimicrobials and modulating host immune systems. Tuberculosis (TB), caused by Mycobacterium tuberculosis, shares these qualities with biofilm infections. To identify genetic determinants of biofilm formation in M. tuberculosis, we performed a small-scale transposon screen using an in...

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PMID: 22123254
DOI: 10.1128/jb.06304-11

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