Article
Additive effect of ANRIL and BRAP polymorphisms on ankle-brachial index in a Taiwanese population.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2012
Tsai Pei-Chien, Liao Yi-Chu, Lin Tsung-Hsien, Hsi Edward, Yang Yi-Hsin, Juo Suh-Hang Hank
Abstract excerpt
BACKGROUND: Genetic variations on chromosome 9p21 have been found to be associated with peripheral artery disease (PAD), but have not been investigated in Asians. The ankle-brachial index (ABI) is a widely-used measurement for PAD. We previously reported the BRAP gene is associated with the ABI, so the aim of the present study was to test whether the ANRIL gene on 9p21 is associated with the ABI and to test an...
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