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Developmental Plasticity and Epigenetic Mechanisms Underpinning Metabolic and Cardiovascular Diseases

1 Jun 2011

Abstract excerpt

The importance of developmental factors in influencing the risk of later-life disease has a strong evidence base derived from multiple epidemiological, clinical and experimental studies in animals and humans. During early life, an organism is able to adjust its phenotypic development in response to environmental cues. Such developmentally plastic responses evolved as a fitness-maximizing strategy to cope with...

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PMID: 22122338
DOI: 10.2217/epi.11.17

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