The role of developmental plasticity and epigenetics in human health.

doi:10.1002/bdrc.20198

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Article

The role of developmental plasticity and epigenetics in human health.

Birth defects research. Part C, Embryo today : reviews - 1 Mar 2011

Gluckman Peter D, Hanson Mark A, Low Felicia M

Abstract excerpt

Considerable epidemiological, experimental and clinical data have amassed showing that the risk of developing disease in later life is dependent on early life conditions, mainly operating within the normative range of developmental exposures. This relationship reflects plastic responses made by the developing organism as an evolved strategy to cope with immediate or predicted circumstances, to maximize fitness in...

Topics

Animals
Epigenesis, Genetic
Epigenomics
Female
Fetal Development
Genetic Predisposition to Disease
Humans
Maternal Nutritional Physiological Phenomena
Metabolic Diseases
Obesity
Pregnancy
Prenatal Care
Prenatal Exposure Delayed Effects
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 21425438
DOI: 10.1002/bdrc.20198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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