The transition of cells of the fission yeast beta-tubulin mutant nda3-311 as seen by freeze-substitution electron microscopy. Requirement of functional tubulin for spindle pole body duplication.

doi:10.1242/jcs.96.2.275

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Article

The transition of cells of the fission yeast beta-tubulin mutant nda3-311 as seen by freeze-substitution electron microscopy. Requirement of functional tubulin for spindle pole body duplication.

Journal of cell science - 1 Jun 1990

Kanbe T, Hiraoka Y, Tanaka K, Yanagida M

Abstract excerpt

A previous fluorescence light-microscopic study showed that the fission yeast cold-sensitive beta-tubulin mutant nda3-311 was arrested with rod-like condensed chromosomes in a mitotic state at the restrictive temperature. Upon transfer to the permissive temperature, a spindle was formed and the n...

Topics

Freezing
Microscopy, Electron
Microtubules
Mitosis
Mutation
Nuclear Envelope
Schizosaccharomyces
Spindle Apparatus
Temperature
Tubulin

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