Article
Association analysis between the -2518MCP-1(A/G) polymorphism and generalized aggressive periodontitis in a Chinese population.
Journal of periodontal research - 1 Jun 2012
Zhu X L, Meng H X, Zhang L, Xu L, Chen Z B, Shi D, Feng X H, Zhang X
Abstract excerpt
BACKGROUND AND OBJECTIVE: It has been suggested that aggressive periodontitis has a genetic basis. Monocyte chemoattractant protein 1 (MCP-1) plays a critical role in the recruitment of monocytes and the development of periodontitis. The -2518MCP-1(A/G) polymorphism has been implicated as a risk or susceptibility factor for a variety of autoimmune conditions and inflammatory diseases. The intent of this...
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