Article
Rationale, objectives, and design of the EUTrigTreat clinical study: a prospective observational study for arrhythmia risk stratification and assessment of interrelationships among repolarization markers and genotype.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 Mar 2012
Seegers Joachim, Vos Marc A, Flevari Panagiota, Willems Rik, Sohns Christian, Vollmann Dirk, Lüthje Lars, Kremastinos Dimitrios T, Floré Vincent, Meine Mathias, Tuinenburg Anton, Myles Rachel C, Simon Dirk, Brockmöller Jürgen, Friede Tim, Hasenfuß Gerd, Lehnart Stephan E, Zabel Markus
Abstract excerpt
AIMS: The EUTrigTreat clinical study has been designed as a prospective multicentre observational study and aims to (i) risk stratify patients with an implantable cardioverter defibrillator (ICD) for mortality and shock risk using multiple novel and established risk markers, (ii) explore a link between repolarization biomarkers and genetics of ion (Ca(2+), Na(+), K(+)) metabolism, (iii) compare the results of...
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