Article
Regulatory interactions between phospholipid synthesis and DNA replication in Caulobacter crescentus.
Journal of bacteriology - 1 Oct 1990
Loewy B, Marczynski G T, Dingwall A, Shapiro L
Abstract excerpt
Several Caulobacter crescentus mutants with lesions in phospholipid biosynthesis have DNA replication phenotypes. A C. crescentus mutant deficient in glycerol 3-phosphate dehydrogenase activity (gpsA) blocks phospholipid synthesis, ceases DNA replication, and loses viability in the absence of a glycerol phosphate supplement. To investigate the interaction between membrane synthesis and DNA replication during a...
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