Article
YS-822A, a new polyene macrolide antibiotic. I. Production, isolation, characterization and biological properties.
The Journal of antibiotics - 1 Aug 1990
Itoh A, Ido J, Iwamoto Y, Goshima E, Miki T, Hasuda K, Hirota H
Abstract excerpt
A new polyene macrolide antibiotic, YS-822A was isolated from the culture filtrate of a mutant strain H-8 of Streptoverticillium eurocidicum var. asterocidicus S-822. Whereas the original S-822 strain produced not only YS-822 substances but also teleocidin as by-product which is well-known as a strong carcinogenic promoter, the mutagenized H-8 strain produced the antibiotic with only a trace amount of teleocidin....
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