Article
Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients.
Blood - 12 Jan 2012
Schönland Stefan O, Hegenbart Ute, Bochtler Tilmann, Mangatter Anja, Hansberg Marion, Ho Anthony D, Lohse Peter, Röcken Christoph
Abstract excerpt
Amyloidoses are characterized by organ deposition of misfolded proteins. This study evaluated immunohistochemistry as a diagnostic tool for the differentiation of amyloid subentities, which is warranted for accurate treatment. A total of 117 patients were systematically investigated by clinical examination, laboratory tests, genotyping, and immunohistochemistry on biopsy specimens. Immunohistochemistry enabled...
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