Article
Gastrointestinal stromal tumors of the stomach.
Surgical oncology clinics of North America - 1 Jan 2012
Bennett Joseph J, Rubino Matthew S
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are relatively rare mesenchymal tumors located within the submucosa of the GI tract. The defining characteristic of GISTs is the presence of the cell-surface antigen CD117 receptor tyrosine kinase, identified by immunohistochemistry. Currently the only cure for GIST is complete surgical resection. Imatinib has revolutionized the treatment of GISTs and has been used as...
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