Article
Comparison of the Salmonella (Ames) test, umu tests, and the SOS Chromotests for detecting genotoxins.
Environmental and molecular mutagenesis - 1 Jan 1990
McDaniels A E, Reyes A L, Wymer L J, Rankin C C, Stelma G N
Abstract excerpt
The limits of detection of 10 genotoxins representing 7 chemical classes with varying structures and modes of action were compared using the Ames test (Salmonella plate-incorporation test) with 2 tester strains, 2 standard colorimetric methods (the umu test and SOS Chromotest), and modifications...
Topics
- Animals
- Dose-Response Relationship, Drug
- Mutagenicity Tests
- Mutagens
- Mutation
- Rats
- SOS Response, Genetics
- Salmonella
- Sensitivity and Specificity
