Article
Yeast: an experimental organism for 21st Century biology.
Genetics - 1 Nov 2011
Botstein David, Fink Gerald R
Abstract excerpt
In this essay, we revisit the status of yeast as a model system for biology. We first summarize important contributions of yeast to eukaryotic biology that we anticipated in 1988 in our first article on the subject. We then describe transformative developments that we did not anticipate, most of which followed the publication of the complete genomic sequence of Saccharomyces cerevisiae in 1996. In the intervening...
Topics
- Animals
- Disease
- Evolution, Molecular
- Gene Regulatory Networks
- Genetic Variation
- Humans
- Protein Interaction Maps
- Saccharomyces cerevisiae