Article
Relation of locus 1p13 rs646776 polymorphism with the risk of preeclampsia.
Hypertension in pregnancy - 1 May 2018
Emam Rana H, Ghattas Maivel H, Mesbah Noha M, Abo-Elmatty Dina M, Mehanna Eman T
Abstract excerpt
OBJECTIVE: This study aimed to assess the relation of locus 1p13 rs646776 (T/C) polymorphism with preeclampsia in Egyptian women. METHODS: The study included 100 healthy pregnant female subjects and 100 preeclampsia patients. The genotypes of the polymorphisms were assessed. Endothelin-1 level was determined in plasma. RESULTS: The major T allele of the 1p13.3 genomic region rs646776 polymorphism had a higher...
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