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Article

Human embryonic development after blastomere removal: a time-lapse analysis

10 Nov 2011

Abstract excerpt

BACKGROUND: Blastomere biopsy of human embryos is performed for preimplantation genetic diagnosis (PGD). The impact on further development is largely unexplored, though studies on mice suggest an influence on the hatching process. The objective of this study was to evaluate the effect of blastomere biopsy on early human embryonic development using time-lapse analysis. METHODS: Embryos from couples undergoing PGD...

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PMID: 22081251
DOI: 10.1093/humrep/der382

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