Article
Exact score distribution computation for ontological similarity searches.
BMC bioinformatics - 12 Nov 2011
Schulz Marcel H, Köhler Sebastian, Bauer Sebastian, Robinson Peter N
Abstract excerpt
BACKGROUND: Semantic similarity searches in ontologies are an important component of many bioinformatic algorithms, e.g., finding functionally related proteins with the Gene Ontology or phenotypically similar diseases with the Human Phenotype Ontology (HPO). We have recently shown that the performance of semantic similarity searches can be improved by ranking results according to the probability of obtaining a...
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