Article

Ontology-based similarity calculations with an improved annotation model

2017-10-06

Abstract excerpt

A typical use case of ontologies is the calculation of similarity scores between items that are annotated with classes of the ontology. For example, in differential diagnostics and disease gene prioritisation, the Human Phenotype Ontology (HPO) is often used to compare a query phenotype profile against gold-standard phenotype profiles of diseases or genes. The latter have long been constructed as flat lists of ont...

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Literature Corpus work: 01562c55-2a27-5500-abc1-752738b92589
DOI: 10.1101/199554

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