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Detection of the tumour suppressor gene <i>TP53</i> and expression of p53, Bcl‐2 and p63 proteins in canine transmissible venereal tumour

21 Feb 2011

Abstract excerpt

Canine transmissible venereal tumour (CTVT) is a neoplasm transmitted among healthy dogs by direct contact with injured skin and/or mucous tissue. This study aimed to identify the TP53 gene, messenger RNA (mRNA) as well as the expression of p53, Bcl-2 and p63 proteins in histological sections of 13 CTVT samples at different stages of evolution. The in situ hybridization (ISH) and in situ reverse transcriptase...

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PMID: 22077405
DOI: 10.1111/j.1476-5829.2010.00260.x

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