Article
Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area.
Journal of human genetics - 1 Oct 2011
Hotta Kikuko, Kitamoto Takuya, Kitamoto Aya, Mizusawa Seiho, Matsuo Tomoaki, Nakata Yoshio, Hyogo Hideyuki, Ochi Hidenori, Kamohara Seika, Miyatake Nobuyuki, Kotani Kazuaki, Komatsu Ryoya, Itoh Naoto, Mineo Ikuo, Wada Jun, Yoneda Masato, Nakajima Atsushi, Funahashi Tohru, Miyazaki Shigeru, Tokunaga Katsuto, Masuzaki Hiroaki, Ueno Takato, Chayama Kazuaki, Hamaguchi Kazuyuki, Yamada Kentaro, Hanafusa Toshiaki, Oikawa Shinichi, Yoshimatsu Hironobu, Sakata Toshiie, Tanaka Kiyoji, Matsuzawa Yuji, Nakao Kazuwa, Sekine Akihiro
Abstract excerpt
Visceral fat accumulation has an important role in increasing morbidity and mortality rate by increasing the risk of developing several metabolic disorders, such as type 2 diabetes, dyslipidemia and hypertension. New genetic loci that contribute to the development of obesity have been identified...
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