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Article

p16/p53 expression and telomerase activity in immortalized human dental pulp cells

15 Nov 2011

Abstract excerpt

INTRODUCTION: Residing within human dental pulp are cells of an ectomesenchymal origin which have the potential to differentiate into odontoblast-like cells. These cells have a limited growth potential owing to the effects of cell senescence. This study examines the effects of immortalizing odontoblast-like cells on cell proliferation and mineralization by comparing transformed dental pulp stem cells (tDPSCs) and...

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PMID: 22067611
DOI: 10.4161/cc.10.22.18093

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