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Efficient immortalization of human dental pulp stem cells with expression of cell cycle regulators with the intact chromosomal condition

2 Mar 2020

Abstract excerpt

Clinical studies have recently demonstrated that autologous transplantation of mobilized dental pulp stem cells is a safe and efficacious potential therapy for pulp regeneration. However, some limitations need to be addressed, such as the high cost of the safety and quality control tests for isolated individual dental pulp cell products before transplantation. Therefore, more efficient in vitro culturing of human...

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PMID: 32119713
DOI: 10.1371/journal.pone.0229996

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