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Article

The role of tyrosine 343 in substrate binding and catalysis by human sulfite oxidase.

The Journal of biological chemistry - 9 Apr 2004

Wilson Heather L, Rajagopalan K V

Abstract excerpt

In the crystal structure of chicken sulfite oxidase, the residue Tyr(322) (Tyr(343) in human sulfite oxidase) was found to directly interact with a bound sulfate molecule and was proposed to have an important role in mediating the substrate specificity and catalytic activity of this molybdoprotein. In order to understand the role of this residue in the catalytic mechanism of sulfite oxidase, steady-state and...

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Identifiers

PMID: 14729666
DOI: 10.1074/jbc.M314288200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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