Article
Cerebellum volume in high-risk offspring from multiplex alcohol dependence families: association with allelic variation in GABRA2 and BDNF.
Psychiatry research - 30 Dec 2011
Hill Shirley Y, Wang Shuhui, Carter Howard, Tessner Kevin, Holmes Brian, McDermott Michael, Zezza Nicholas, Stiffler Scott
Abstract excerpt
Offspring from families with multiple cases of alcohol dependence have a greater likelihood of developing alcohol dependence (AD) and related substance use disorders. Greater susceptibility for developing these disorders may be related to structural differences in brain circuits that influence the salience of rewards or modify the efficiency of information processing and AD susceptibility. We examined the...
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