Article
Use of genetic and nongenetic factors in warfarin dosing algorithms.
Pharmacogenomics - 1 Jul 2007
Wu Alan H B
Abstract excerpt
Despite the fact that warfarin has been used as an anticoagulant for many years, the safety profile for this drug has been poor. Inappropriate dosing continues to contribute to significant morbidity and mortality due to thrombotic disease and bleeding. Therefore, there is a need for the development, characterization and implementation of dosing algorithms using a patient's demographic information and genotype....
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