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Article

Biofilm and planktonic pneumococci demonstrate disparate immunoreactivity to human convalescent sera.

BMC microbiology - 2 Nov 2011

Sanchez Carlos J, Hurtgen Brady J, Lizcano Anel, Shivshankar Pooja, Cole Garry T, Orihuela Carlos J

Abstract excerpt

BACKGROUND: Streptococcus pneumoniae (the pneumococcus) is the leading cause of otitis media, community-acquired pneumonia (CAP), sepsis, and meningitis. It is now evident that S. pneumoniae forms biofilms during nasopharyngeal colonization; the former which facilitates persistence, the latter, a prerequisite for subsequent development of invasive disease. Proteomic evaluation of S. pneumoniae suggests the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22047041
DOI: 10.1186/1471-2180-11-245
PMCID: PMC3216281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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