Article
Pronounced metabolic changes in adaptation to biofilm growth by Streptococcus pneumoniae.
PloS one - 1 Jan 2014
Allan Raymond N, Skipp Paul, Jefferies Johanna, Clarke Stuart C, Faust Saul N, Hall-Stoodley Luanne, Webb Jeremy
Abstract excerpt
Streptococcus pneumoniae accounts for a significant global burden of morbidity and mortality and biofilm development is increasingly recognised as important for colonization and infection. Analysis of protein expression patterns during biofilm development may therefore provide valuable insights to the understanding of pneumococcal persistence strategies and to improve vaccines. iTRAQ (isobaric tagging for...
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