Article
Molecular differentiation of historic phage-type 80/81 and contemporary epidemic Staphylococcus aureus.
Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 2011
DeLeo Frank R, Kennedy Adam D, Chen Liang, Bubeck Wardenburg Juliane, Kobayashi Scott D, Mathema Barun, Braughton Kevin R, Whitney Adeline R, Villaruz Amer E, Martens Craig A, Porcella Stephen F, McGavin Martin J, Otto Michael, Musser James M, Kreiswirth Barry N
Abstract excerpt
Staphylococcus aureus is a bacterial pathogen known to cause infections in epidemic waves. One such epidemic was caused by a clone known as phage-type 80/81, a penicillin-resistant strain that rose to world prominence in the late 1950s. The molecular underpinnings of the phage-type 80/81 outbreak have remained unknown for decades, nor is it understood why related S. aureus clones became epidemic in hospitals in...
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