Paget's disease of bone.

Abstract excerpt

OBJECTIVES: To review recent advance in understanding the causation and management of Paget's disease. DESIGN AND METHODS: We review recent publications concerning the aetiology of the disease and the use of biochemical markers of bone turnover in diagnosis and treatment. RESULTS: Epidemiologic studies suggest that Paget's disease is decreasing in prevalence and severity (implying that environmental factors are...

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