Article
Regional selection acting on the OFD1 gene family.
PloS one - 1 Jan 2011
Chang Ti-Cheng, Klabnik Jessica L, Liu Wan-Sheng
Abstract excerpt
The OFD1 (oral-facial-digital, type 1) gene is implicated in several developmental disorders in humans. The X-linked OFD1 (OFD1X) is conserved in Eutheria. Knowledge about the Y-linked paralog (OFD1Y) is limited. In this study, we identified an OFD1Y on the bovine Y chromosome, which is expressed differentially from the bovine OFD1X. Phylogenetic analysis indicated that: a) the eutherian OFD1X and OFD1Y were...
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