Discordance of oral-facial-digital syndrome type 1 in monozygotic twin girls.

doi:10.1002/(sici)1096-8628(19990917)86:3<269::aid-ajmg14>3.0.co;2-g

Back to search

Article

Discordance of oral-facial-digital syndrome type 1 in monozygotic twin girls.

American journal of medical genetics - 17 Sept 1999

Shotelersuk V, Tifft C J, Vacha S, Peters K F, Biesecker L G

Abstract excerpt

The oral-facial-digital syndrome type 1 (OFD1) includes limb, facial, intraoral malformations and the gene for the disorder was recently mapped to Xp22.3-p22.2. We report on monozygotic twin girls discordant for OFD1. Monozygosity is supported by placental pathology (monochorionic diamniotic) and...

Topics

Child
Diseases in Twins
Dosage Compensation, Genetic
Female
Humans
Mutation
Orofaciodigital Syndromes
Twins, Monozygotic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.