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The impact of a Dysbindin schizophrenia susceptibility variant on fiber tract integrity in healthy individuals: a TBSS-based diffusion tensor imaging study.

NeuroImage - 2 Apr 2012

Nickl-Jockschat Thomas, Stöcker Tony, Markov Valentin, Krug Axel, Huang Ruihuang, Schneider Frank, Habel Ute, Zerres Klaus, Nöthen Markus M, Treutlein Jens, Rietschel Marcella, Shah N Jon, Kircher Tilo

Abstract excerpt

Schizophrenia is a severe neuropsychiatric disorder with high heritability, though its exact etiopathogenesis is yet unknown. An increasing number of studies point to the importance of white matter anomalies in the pathophysiology of schizophrenia. While several studies have identified the impact of schizophrenia susceptibility gene variants on gray matter anatomy in both schizophrenia patients and healthy risk...

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PMID: 22019876
DOI: 10.1016/j.neuroimage.2011.10.012

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