Article
Cardiac levels of NOS1AP RNA from right ventricular tissue recovered during lead extraction.
Heart rhythm - 1 Mar 2012
Saba Samir, Mehdi Haider, Shah Hemal, Islam Zahid, Aoun Elie, Termanini Sammy, Mahjoub Reem, Aleong Ryan, McTiernan Charles F, London Barry
Abstract excerpt
BACKGROUND: There is a scarcity of cardiac tissue available for research. OBJECTIVE: (1) To investigate the feasibility of obtaining myocardial tissue from extracted pacemaker and defibrillator leads for gene expression analysis and (2) to examine the nitric oxide 1 adaptor protein (NOS1AP) RNA expression as a function of patient genotype. METHODS: Seventeen patients (age = 56 ± 20 years; 12 men; 5 pacemakers; 12...
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