Article
Economic high-throughput-identification of influenza A subtypes from clinical specimens with a DNA-oligonucleotide microarray in an outbreak situation.
Molecular and cellular probes - 1 Feb 2012
Bandt Dirk, Monecke Stefan, Scott Carly, Gall Astrid, Hoffmann Bernd, Ehricht Ralf
Abstract excerpt
Influenza A surface proteins H (haemagglutinin) and N (neuraminidase) occur in sixteen and nine distinct genotypes, respectively. The need for a timely production of vaccinations in case of pandemics or seasonal epidemics requires rapid typing methods for the determination of these alleles. The aim of the present study was to develop and improve a rapid and economic assay for determining H and N subtypes of...
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