Article
Universal oligonucleotide microarray for sub-typing of Influenza A virus.
PloS one - 29 Apr 2011
Ryabinin Vladimir A, Kostina Elena V, Maksakova Galiya A, Neverov Alexander A, Chumakov Konstantin M, Sinyakov Alexander N
Abstract excerpt
A universal microchip was developed for genotyping Influenza A viruses. It contains two sets of oligonucleotide probes allowing viruses to be classified by the subtypes of hemagglutinin (H1-H13, H15, H16) and neuraminidase (N1-N9). Additional sets of probes are used to detect H1N1 swine influenza viruses. Selection of probes was done in two steps. Initially, amino acid sequences specific to each subtype were...
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