Article
Risk of nasopharyngeal carcinoma associated with polymorphic lactotransferrin haplotypes.
Medical oncology (Northwood, London, England) - 1 Sept 2012
Zhou Yanhong, Wang Wei, Zheng Danwei, Peng Shuping, Xiong Wei, Ma Jian, Zeng Zhaoyang, Wu Minghua, Zhou Ming, Xiang Juanjuan, Xiang Bo, Li Xiaoling, Li Xiayu, Li Guiyuan
Abstract excerpt
Lactotransferrin (LTF) is a component of the nonspecific immune system, having antimicrobial properties against bacteria, fungi, and several viruses. The gene coding for LTF is polymorphic, with the occurrence of several common alleles in the general population. Our previous study found that LTF inhibited nasopharyngeal carcinoma (NPC) cell proliferation in vitro and in vivo. To better understand one possible...
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