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Article

MYCT1-TV, a novel MYCT1 transcript, is regulated by c-Myc and may participate in laryngeal carcinogenesis.

PloS one - 1 Jan 2011

Fu Shuang, Guo Yan, Chen Hong, Xu Zhen-Ming, Qiu Guang-Bin, Zhong Ming, Sun Kai-Lai, Fu Wei-Neng

Abstract excerpt

BACKGROUND: MYCT1, a putative target of c-Myc, is a novel candidate tumor suppressor gene cloned from laryngeal squamous cell carcinoma (LSCC). Its transcriptional regulation and biological effects on LSCC have not been clarified. METHODOLOGY/PRINCIPAL FINDINGS: Using RACE assay, we cloned a 1106 bp transcript named Myc target 1 transcript variant 1 (MYCT1-TV) and confirmed its transcriptional start site was...

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Share to Cloning, Molecular
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to HEK293 Cells

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Share to Proto-Oncogene Proteins c-myc

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Source

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Identifiers

PMID: 21998677
DOI: 10.1371/journal.pone.0025648
PMCID: PMC3187795

Genes

MYCT1

Provenance

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