Article
Association of ACE2 variant rs4646188 with the risks of atrial fibrillation and cardioembolic stroke in Uygur patients with type 2 diabetes.
BMC cardiovascular disorders - 18 Feb 2021
Liu Cheng, Pei Jingxian, Lai Yanxian, Guan Tianwang, Zeyaweiding Abudurexiti, Maimaiti Tutiguli, Zhao Haiyan, Shen Yan
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Type 2 diabetes (T2D) is an independent risk factor for AF. The cardioembolic stroke (CS) risk is increased when both conditions coexist. Whether angiotensin-converting enzyme 2 (ACE2) genetic variants predict increased risks AF and CS in Uygur patients with T2D remain elusive. METHODS: A total of 547 Uygur subjects (272 controls and 275...
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