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Article

Single Nucleotide Polymorphisms Associated with AA-Amyloidosis in Siamese and Oriental Shorthair Cats.

Genes - 25 Nov 2023

Esders Stella L, Hülskötter Kirsten, Schreiner Tom, Wohlsein Peter, Schmitz Jessica, Bräsen Jan H, Distl Ottmar

Abstract excerpt

AA-amyloidosis in Siamese and Oriental shorthair cats is a lethal condition in which amyloid deposits accumulate systemically, especially in the liver and the thyroid gland. The age at death of affected cats varies between one and seven years. A previous study indicated a complex mode of inheritance involving a major locus. In the present study, we performed a multi-locus genome-wide association study (GWAS)...

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Identifiers

PMID: 38136948
DOI: 10.3390/genes14122126
PMCID: PMC10742459

Genes

SAA1

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