Article
Role of genetic variants in the gene encoding lipocalin-2 in the development of elevated blood pressure.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2011
Ong Kwok-Leung, Tso Annette W K, Cherny Stacey S, Sham Pak-Chung, Lam Tai-Hing, Lam Karen S L, Cheung Bernard M Y
Abstract excerpt
Lipocalin-2 is recently recognized as a biomarker of obesity and inflammation, which are both risk factors for hypertension. We therefore investigated the association of common single nucleotide polymorphisms (SNPs) in the gene encoding lipocalin-2 (LCN2) with elevated blood pressure (BP) in Hong Kong Chinese. Five tagging SNPs were genotyped in 1936 subjects from the Hong Kong Cardiovascular Risk Factor...
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