Article
TRAF1/C5, eNOS, C1q, but not STAT4 and PTPN22 gene polymorphisms are associated with genetic susceptibility to systemic lupus erythematosus in Turkey.
Human immunology - 1 Dec 2011
Zervou Maria I, Vazgiourakis Vassilios M, Yilmaz Neslihan, Kontaki Elena, Trouw Leendert A, Toes Rene E, Bicakcigil Muge, Boumpas Dimitrios T, Yavuz Sule, Goulielmos George N
Abstract excerpt
A significant source of variability in the literature on systemic lupus erythematosus (SLE) susceptibility genes has been the inability to replicate genetic findings across different racial or ethnic groups. We investigated whether a single nucleotide polymorphism (SNP) of the STAT4 (rs7574865), PTPN22 (rs2476601), TRAF1/C5 (rs10818488), and C1q (rs292001) genes as well as the 27-bp VNTR polymorphism on intron 4...
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