Article
Empirical evaluation reveals best fit of a logistic mutation model for human Y-chromosomal microsatellites.
Genetics - 1 Dec 2011
Jochens Arne, Caliebe Amke, Rösler Uwe, Krawczak Michael
Abstract excerpt
The rate of microsatellite mutation is dependent upon both the allele length and the repeat motif, but the exact nature of this relationship is still unknown. We analyzed data on the inheritance of human Y-chromosomal microsatellites in father-son duos, taken from 24 published reports and comprising 15,285 directly observable meioses. At the six microsatellites analyzed (DYS19, DYS389I, DYS390, DYS391, DYS392,...
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